What is VLDL cholesterol? Can it be harmful?

Answer From Francisco Lopez-Jimenez, M.D.

Very-low-density lipoprotein, also called VLDL, cholesterol is produced in the liver and released into the bloodstream to supply body tissues with a type of fat called triglycerides.

There are several types of lipoproteins that transport cholesterol throughout the body. Lipoproteins are made up of cholesterol, fats or triglycerides and proteins called apolipoproteins in varying amounts. About half of a VLDL particle is made up of triglycerides.

High levels of VLDL cholesterol have been associated with the development of plaque deposits on artery walls, which narrow the passage and restrict blood flow. This increases the risk of cardiovascular disease.

There’s no simple, direct way to measure VLDL cholesterol, which is why it’s typically not mentioned during a routine cholesterol screening. VLDL cholesterol is usually estimated as a percentage of the triglyceride value. An elevated VLDL cholesterol level is more than 30 milligrams per deciliter.

The best way to lower your VLDL cholesterol is to lower your triglycerides. Losing weight and being active regularly are key, and you also might want to avoid sugary food and alcohol in particular. Medicines also can help.

With

Francisco Lopez-Jimenez, M.D.

 

From Mayo Clinic to your inbox

Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview.

We use the data you provide to deliver you the content you requested. To provide you with the most relevant and helpful information, we may combine your email and website data with other information we have about you. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our Notice of Privacy Practices. You may opt out of email communications at any time by clicking on the unsubscribe link in the email.